This discovery proved an exception to the “central dogma” of genetic theory, which states that the information encoded in genes always flows unidirectionally from DNA to RNA (and thence to proteins) and cannot be reversed. Let us know if you have suggestions to improve this article (requires login). The discovery that the information in RNA can be transferred to DNA meant that the generally accepted rule that genetic information was only transferred in one direction - from DNA to RNA, to protein - had to be modified. He worked with Dulbecco at the Salk Institute in La Jolla, California (1965–68), studying the mechanism of replication of the poliovirus. David Baltimore The coauthor of the article, Thereza Imanishi-Kari, was accused of falsifying data published in the paper. In Boston, Baltimore and Huang, who had married, showed that VSV, an RNA virus, reproduced itself by means of an unusual enzyme (an RNA-dependent RNA polymerase) that copies RNA by a process not involving DNA. Premium Membership is now 50% off! Tasked with a mission to manage Alfred Nobel's fortune and has ultimate responsibility for fulfilling the intentions of Nobel's will.
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